Kyler Murray, Arizona Cardinals (vs. San Francisco)
The Cardinals are coming off of a bye week and a big win over the Pittsburgh Steelers before that. Plus, they will be getting this game at home.
But that is probably where the positives end.
The San Francisco 49ers have allowed the third-lowest amount of points to QBs this season and they are surging, looking to be the No. 1 seed in the NFC.
Kyler Murray will be making his fifth start of the season and while he hasn't been bad in his four previous starts, he hasn't been excellent either, throwing three touchdowns and two interceptions while completed just over 60 percent of his throws.
He has not made a start against the 49ers since October 2021 and he has never thrown for more than 247 yards in a game against the divisional opponent. But this matchup just doesn't look good unless you're banking on Murray to be throwing the ball around a lot as the Cardinals try to play catch-up all day.
In the fantasy playoffs, you should want more than that.