Best Fantasy Football matchups for Week 4

How to boost your lineup based on their matchups.

New York Giants v San Francisco 49ers
New York Giants v San Francisco 49ers / Michael Zagaris/GettyImages
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Running Backs

Alexander Mattison - Vikings vs. PANTHERS - RB14 - Projected Points 11.4

Mattison had 93 yards rushing last week against the Chargers who this year have given up 408 combined rushing and receiving yards to running backs. This week he is playing against a team that has given up 446 combined yards. The Panthers have also given up 6 touchdowns in three games to running backs. Only the Broncos have given up more. Since the Panthers have surrendered the third-most fantasy points to RBs this year, this should be a great matchup for Mattison.

D’Andre Swift - EAGLES vs. Commanders - RB15 - Projected Points 13

Swift has taken hold of the Eagles backfield. Even though he isn’t getting the touchdowns, he has had 305 yards rushing in the last two games. The Eagles play at home and are eight-point favorites. This is a team that runs more than they pass and Swift has touched the ball more than any other Eagle so far.