Brandon Aiyuk (vs. Philadelphia Eagles)
Brandon Aiyuk has been the San Francisco 49ers top wide receiver this season and in a big matchup that could decide the NFC, they are going to lean heavily on Aiyuk. On the season, he has 881 receiving yards and five touchdowns but has over 250 receiving yards and three of those touchdowns in the past three weeks.
Meanwhile, the Eagles' defense has struggled against wide receivers over the last three games, allowing 620 receiving yards and five touchdowns to wide receivers. According to NFL Fantasy, the Eagles are giving up the third most points per game to wide receivers over the last month.
If there is a concern with Aiyuk it is that he does not see a high volume of targets as he only has 13 over the past three weeks. However, this game could end up being a high-scoring matchup and if that is the case expect Brock Purdy to throw more than he has recently and this sets up Aiyuk to have a big game.